Rome’s cruise port is in Civitavecchia, about an hour outside the city.
It is one of the busiest in Europe and offers a wide range of Western and Eastern Mediterranean cruises. 7 nights is by far the most common cruise duration, but anything from 1 night to 20+ is available.
As a major cruise port, Trans-Atlantic repositionings, Suez Canal transits to the Middle East, and world cruise segments are semi-regular options too. With few exceptions, these are all 14+ nights.